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Understanding Joint Degeneration: Causes and Prevention of Osteoarthritis

Medically Reviewed by

Mar 5, 2025

Your joints might feel fine today, but fast forward a few years, and things could be very different. Joint degeneration doesn’t happen overnight—it creeps up slowly, wearing down the cartilage that keeps your movements smooth and pain-free. One day, simple activities like walking up the stairs or gripping a coffee mug might become agonizing.

Osteoarthritis, the most common form of joint degeneration, affects millions, and once the damage is done, there’s no turning back. The good news? You can take steps now to protect your joints and prevent long-term suffering. Understanding the causes is the first step.

What is joint degeneration?

“Joint degeneration and osteoarthritis are pervasive - every joint and every person can develop this painful condition. The physicians and surgeons of OINJ can diagnose this condition and individualize treatment for you.”- Dr. Christian Zaino

Joint degeneration refers to the gradual breakdown of cartilage, the smooth tissue that cushions bones at the joints. Over time, this protective layer wears down, leading to pain, stiffness, and inflammation. The most common form of joint degeneration is osteoarthritis, a condition in which cartilage deterioration causes bones to rub against each other, triggering discomfort and mobility issues. 

Medically speaking, this process occurs when the body’s ability to repair joint tissues slows down. Factors like aging, repetitive stress, and inflammation contribute to cartilage breakdown. As the cushioning diminishes, joints become less flexible, causing swelling, stiffness, and, in severe cases, bone spurs or joint deformities.

What Causes Osteoarthritis?

Osteoarthritis doesn’t happen overnight—it develops over time due to a combination of wear and tear, lifestyle factors, and underlying health conditions. While aging is a primary contributor, several other factors can accelerate joint damage. Understanding this is the key to your efforts to avoid joint pain later in life.

So, the common causes of osteoarthritis are:

  • Cartilage Wear and Tear: Daily movements and repetitive stress gradually wear down the cartilage, making joints more vulnerable.
  • Joint Injuries: Past injuries, such as fractures or ligament damage, can lead to early joint degeneration, even if they healed years ago.
  • Excess Weight: Extra body weight puts more strain on weight-bearing joints like knees and hips, accelerating cartilage breakdown.
  • Genetics: Some people inherit weaker joint structures or a predisposition to cartilage deterioration.
  • Inflammation and Autoimmune Conditions: Chronic inflammation from conditions like rheumatoid arthritis can weaken joint tissues and speed up osteoarthritis.
  • Poor Posture or Joint Misalignment: Incorrect posture or uneven stress on joints can lead to abnormal wear patterns and faster degeneration.

So, who is at higher risk of joint degeneration?

  • Older Adults: Cartilage naturally wears down with age, making osteoarthritis more common in people over 50.
  • Athletes and Manual Laborers: High-impact activities, heavy lifting, and repetitive joint use increase wear and tear.
  • People with a Family History: Genetic factors can make some individuals more prone to osteoarthritis.
  • Individuals with Metabolic Disorders: Conditions like diabetes and high cholesterol can contribute to joint inflammation and degeneration.
  • Women: Hormonal changes, especially after menopause, may increase the risk of developing osteoarthritis.

While osteoarthritis can’t always be avoided, understanding its causes and risk factors can help you take steps to protect your joints before serious damage occurs.

How do you treat degenerative joint disease?

Once joint degeneration sets in, there’s no way to completely reverse the damage, but there are effective treatments to manage pain, improve mobility, and slow the progression of osteoarthritis. A combination of medical treatments, lifestyle changes, and targeted therapies can help keep your joints functional and reduce discomfort.

Medical and Therapeutic Treatments

  • Pain Relievers and Anti-Inflammatory Medications:Over-the-counter NSAIDs or prescription medications help reduce pain and swelling.
  • Physical Therapy: Strengthening muscles around the joint improves support and reduces strain on damaged cartilage.
  • Joint Injections: Corticosteroid or hyaluronic acid injections can provide temporary pain relief and improve movement.
  • Bracing or Assistive Devices: Knee braces, orthotics, or walking aids can reduce pressure on affected joints.
  • Surgical Interventions: In severe cases, procedures like joint resurfacing or total joint replacement may be necessary. 

Moreover, there are quite a few joint health tips for managing symptoms. For instance:

  • Maintain a Healthy Weight: Less body weight means less strain on weight-bearing joints like knees and hips.
  • Stay Active with Low-Impact Exercise: Activities like swimming, cycling, or yoga help maintain joint mobility without excessive stress.
  • Follow an Anti-Inflammatory Diet: Foods rich in omega-3s, antioxidants, and healthy fats can help reduce joint inflammation.
  • Use Heat and Cold Therapy: Heat relaxes stiff joints, while ice helps reduce swelling and pain.
  • Prioritize Proper Posture and Ergonomics: Reducing unnecessary joint strain in daily activities can slow degeneration.

While joint degeneration can’t be fully cured, a proactive approach to treatment and lifestyle adjustments can make a significant difference in preserving joint function and quality of life.

What should I do if I have osteoarthritis?

If you’ve been diagnosed with osteoarthritis, the first step is to take control of your joint health by making lifestyle adjustments that support mobility and reduce discomfort. Staying active may seem counterintuitive when your joints hurt, but movement is essential to keeping them functional. Low-impact activities like swimming or walking help maintain flexibility without putting excessive strain on damaged cartilage. Combining exercise with weight management can further alleviate stress on weight-bearing joints, making daily movements less painful over time.

Osteoarthritis pain relief often requires a combination of medical treatment and self-care. Over-the-counter pain relievers, prescription medications, or joint injections can help manage inflammation, while physical therapy strengthens surrounding muscles for better joint support. Additionally, applying heat before activity can loosen stiff joints, and using ice afterward helps reduce swelling. A balanced diet rich in anti-inflammatory foods can also help slow disease progression and improve overall joint health.

It’s also important to recognize when conservative treatments are insufficient. If osteoarthritis pain starts interfering with daily life, consulting a specialist about advanced treatment options like assistive devices or even surgery may be necessary. While osteoarthritis is a lifelong condition, taking proactive steps can help you stay mobile, manage pain, and maintain a better quality of life for years.

Wrap up

Joint degeneration is a slow but progressive condition that, if left unchecked, can significantly impact mobility and quality of life. While osteoarthritis has no cure, understanding its causes and taking preventive measures can make a real difference. By staying active, maintaining a healthy weight, and seeking proper treatment, you can manage symptoms and protect your joints in the long run. The key is to act early before the damage becomes irreversible.

Take control of your joint health—schedule a consultation with the Orthopedic Institute of NJ today to learn how to prevent osteoarthritis.

Joint degeneration and osteoarthritis are pervasive - every joint and every person can develop this painful condition. The physicians and surgeons of OINJ can diagnose this condition and individualize treatment for you.
Christian J. Zaino, MD Christian J. Zaino, MD, Orthopedic Surgery, Hand & Wrist
Hand & Upper Extremity Center
This article was reviewed and approved by an orthopedic surgeon as we place a high premium on accuracy for our patients and potential patients.